ATLANTA – A phase I clinical trial conducted by Emory University, in collaboration with researchers from the Georgia Institute of Technology, has found that influenza vaccination using a patch with dissolvable microneedles was safe and well-tolerated by study participants, according to results published in a recent issue of The Lancet medical journal. The study also found that the patch was equally effective in generating immunity against influenza and was strongly preferred by study participants over vaccination with a hypodermic needle and syringe. “Having the option of a flu vaccine that can be easily and painlessly self-administered could increase coverage and protection by this important vaccine,” said Dr. Nadine Rouphael, principal investigator of the clinical trial. The researchers also are working to develop microneedle patches for use with other vaccines, including measles, rubella and polio.
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